This paper proposes an application of mixed Reality Technology in 3d Virtual instructional media in order to reduce the problems of learning with imagination learning without seeing and failure to understand complicated content The purposively sampling group comsisted of 30 mathayom 2 students from Trimit Witthayalai School. Results showed students achievements after leaming with 3d media were signicantly higher than students achievements before learning at the level of .01 Evaluation of satisfaction in 3d Virtual instructional media was in goof and very good level.