The purpose of this research was to: 1) use Multimedia Development to instruct Secondary 1 students learning Basic Sewing in Home Economics subject 2) compare academic achievement of students taught with the multimedia instruction and students taught with the conventional method and 3) study student satisfaction of the Multimedia Development technique Basic Sewing in Home Economics subject. A sample of 60 secondary 1 students attending Sinakharinwirot University Prasanmit Demonstration School was chosen using Cluster Random Sampling and were classified into 2 groups of 30 students; the first being the experimental group instructed with the Multimedia Development technique and the second being the control group instructed with conventional methods. The instruments of this research include lesson plans multimedia an evaluation form to track the multimedia efficiency a practice evaluation form and a questionnaire surveying student satisfaction. The statistics used for the data analysis were percentages mean standard deviation and a t-test. The results were as follows: 1) using Multimedia Development to instruct Secondary 1 students learning Basic Sewing in Home Economics subject achieved the efficiency of 82.14/80.06 2) the students taught with the multimedia technique have greater after learning achievement than those taught with the conventional method; statistical significance was at the .05 level and 3) the student satisfaction of the Multimedia Development technique Basic Sewing in Home Economics subject in high level is (x̅ = 4.42S.D. = 0.54)