This research focuses on development of Multimedia and Interactive System through Network for Learning of Opportunities School. This system used as a channel for students to learn outside the classroom and used as a teaching management tool for teacher. Tools for system development were program Microsoft Visual Studio. Database management system with MySQL. Write commands to work with PHP and Java scripts. For evaluating efficiency of the developed system this research used Sample group to answer questionnaires. The population of research is teachers and students of the Bankamwa school (Weboonratsamakee) in totals 97 people. The result of experiment shows that group is recognized the performance of system in the higher level and the system has efficiency of working.