The objective of this research was the comparison of the efficiency between Papier Mache model of components of human ears and standard medical model. The method was composed of the quality determination questionnaire of the established Papier Mache model by anatomy medical experts. The efficiency test of the Papier Mache model was performed by a group of 30 third years’ medical students. The statistics used in data analysis were mean standard deviation and T-test (T-test Independent). This research of Papier Mache model meets the quality of the standard model from foreign countries and can be used as the model for the instruction education.

The aims of this study were developed geopolymer matrix for controlled release amoxicillin antibiotic drug in the in vitro gastric and intestines (pH 1 and pH 6.8 temperature 37 ºC conditions). Three formulations of geopolymer tablets (GeAmSF5 GeAmSF7.5 and GeAmSF10) which different silica fume content were used in this study. Geopolymer tablets were measured compressive strength and characterized by using 3D laser microscope Scanning electron microscope (SEM) X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR). The amoxicillin release was analyzed by UV-VIS spectrophotometer. It was found that amoxicillin in geopolymer tablet was more resistance with various extraction solvents (ethanol water 50 oC pH 1 and 12 solutions) than amoxicillin commercial tablet in 2 hours. Moreover the amoxicillin constantly release from geopolymer matrix after 3 hours in both in vitro gastric and intestines. However amoxicillin was more release in gastric than intestines condition due to the strong acid leached aluminum ion causing damages geopolymer structure. Mathematical modeling of amoxicillin release from geopolymer matrix was fitted best with Higuchi model indicating diffusion of the drug out of matrix.