จำนวน Repository ( 4 )
การเตรียมและศึกษาสมบัติทางโครงสร้างและแม่เหล็กของอนุภาคคอมโพสิตระดับนาโนเมตรของไฮดรอกซีอะพาไทต์และซิงก์เฟอไรท์ เพื่อประยุกต์ใช้ในการรักษามะเร็งในอนาคต
A promising composite of zinc ferrite (ZnFe2O4) and bioactive hydroxyapatite (Ca10(PO4)6(OH)2 ;HAp) has expected to potential for future bone reinforcing formation. In present study zinc ferrite and hydroxyapatite composite was prepared by solid state reaction route for easier control of structural and magnetic characteristics and with low cost. Hydroxyapatite powder was synthesized by precipitation method from chicken eggshell. Mixed powders with varying ZnFe2O4/HAp weight ratios from 2-10 wt% were milled together and uniaxially pressed and then sintered at 1200 oC for 3 hours. The XRD results showing no other phases of composite with only HAp and ZnFe2O4 phases were identified indicating high stability of HAp property. Phase fractions of ZnFe2O4 were found to increase from 10.8 to 18.73 wt% with increasing content of ZnFe2O4. FT-IR results of ZnFe2O4/HAp composite were only revealed vibration bands of standard HAp phase. This may due to the overlapping of the ZnFe2O4 vibrational bands with HAp bands. However their intense variations observed in HAp vibrational bands indicated the interaction between ZnFe2O4 and HAp. The surface morphology of these ZnFe2O4/HAp composite exhibited primary grain in nano scale with enhanced pore structure and Interconnectivity when ZnFe2O4 weight ratios increased; indicating high surface area for cell attachment and better good cell growth and differentiation. The higher saturation magnetization as well as higher super paramagnetic behavior could be easily altered by increasing ZnFe2O4 content in the composite.
The potential development of Ficus hispida Linn use to traditional herbs and cancer prevention for generate knowledge and heritage of local wisdom
The study used the bark leaves and fruit of Ficus hispida Linn to separation by Maceration and sequential extraction method with hexane ethyl acetate and methanol to crude extracts. Crude extracts were assessed for their antioxidant activities tested using DPPH radical scavenging assay total phenolic contents tested using the Folin–Ciocalteu method cytotoxic activity against oral cavity cancer (KB) human small cell lung cancer (NCI-H187) and breast cancer (MCF-7) cancer cell lines tested using the resazurin microplate assay (REMA). The results showed that 1. Crude methanol extracts from the fruit exhibited free radical scavenging effect on the DPPH assay with IC50 value of 27 g/ml with the total phenolic contents value of 102.39 mg GAE/g dw of standard BHT. 2. Crude hexane extracts from the bark showed highest inhibited the growth of Vibrio paraheamolyticus crude ethyl acetate extracts from the bark showed highest inhibited the growth of Streptococcus mutans ATCC 27175 and crude methanol extracts from the leaves showed highest inhibited the growth of Vibrio cholerae most with MIC value of 7.80 g/ml. 3. Crude ethyl acetate and methanol extracts from F. Hispida exhibited inhibitory effect against oral cavity cancer (KB) human small cell lung cancer (NCI-H187) and breast cancer (MCF-7) cancer cell lines. These data support traditional uses of F. Hispida in folk medicine
Chemical composition and biological activity of ficus hispida linn
To study the effect biological activity of a fig tree extract using Sequential Extraction and use of fennentation Maceration using solvent 3 types of hexane ethyl acid state and methanol to extract 12 Chanin made. tested oral cancer cells (human mouth carcinoma: KB) lung cancer cells (human small cell lung cancer: NCI-HI87) breast cancer (breast cancer: MCF-7) anti-malarial. (Anti-malaria; Plasmodium falciparum) Microculture Radioisotope Technique used to test anti-tuberculosis (Anti-Mycobacterium. tuberculosis. anti-TB) to the Green fluorescent protein microplate assay (GFPMA). The results showed that extracts of the fig tree has anti-cancer Including breast cancer lung cancer and oral cancer. Extracts of the fig tree does not have anti-tuberculosis and extracts of the fig tree shows some anti-malarial. In further research should study the molecular and biological activity of the fig tree from the roots seeds leaves flowers and fruit to the biological activity ofthe data for a selection of extracts from medicinal plants to make. Purification and further develop research in the next commercial.
Cytotoxic and Antimicrobial Activities of Mushrooms and Medicinal Plant
Extractions of bioactive constituent from the Russula eburneureolata Hongo.stem bark of Xylocarpus gangeticus Parking. root and leaf of Walsura trichostemon Miq.and Parinari anamense Hancewith a polarity sequential extraction and maceration technique with hexaneethyl acetate and methanol.respectively.Crude extract was employed to evaluate the biological activity for their cytotoxic activity against human mouth carcinoma (KB) human small cell lung cancer (NCI-H187) and breast cancer (MCF-7)cancer cell lines tested using the Resazurin microplate assay (REMA).Antimycobacterial activity against Mycobacterium tuberculosis H37Ra strain (Anti-TB) using the Green Fluirescent Protein Microplate Assay (GFPMA)