This research aimed to study the properties of interlocking block mixed with stone dust in the ratio of 0, 10, 20 and 30 by weight of cement. The ratio of cement to lateritic soil was 1: 6 by weight. The optimum moisture content (OMC) was obtained from the Standard Proctor Test. Square interlocking block formwork of round-flowered type with holes, size 12.5 x 10 x 25 centimeters, was formed by a manual compression molding machine. Conduct tests for the compressive strength, density, and water absorption of interlocking block mixed with stone dust in compliance with the Thai community product standard of interlocking block (TCPS 602-2004). The results of the study found that the use of stone dust of cement in the production of interlocking block resulting in increased the water absorption and density, but the compressive strength were decreased. All mixing ratios of interlocking block have the measured properties in accordance with the TCPS 602-2004 for non-load bearing type. The percentage of displacement of stone dust suitable for the production of interlocking block this time is 30% with compressive strength of 4.36 MPa, density of 1,707 kilograms per cubic meter and absorption of water 253 kilograms per cubic meter, respectively, at a curing life of 28 days.